HLA-B27 Nucleic Acid Test Kit na Mutum (Hanyar PCR ta Fluorescence)

Human Leukocyte Antigen B27(HLA-B27) Polymerase Chain Reaction(PCR) Fluorescence Detection Kit

Human Leukocyte Antigen-B27 (HLA-B27) kwayoyin halitta ne na mutum babban Histocompatibility Complex (MHC,) wani allele na B wuri a cikin aji I kwayoyin halitta.

Binciken ya nuna cewa Ankylosing spondylitis (AS) cutar autoimmune ce ta kullum da ke da alaƙa da kwayar halitta ta HLA-B27, wanda ke da alaƙa da abubuwan kwayoyin halitta. Dangane da kididdigar, akwai kimanin mutane miliyan 4 da ke fama da cututtukan AS a kasar Sin, fiye da kashi 90% na mutanen da ke fama da cututtukan AS suna bayyana HLA-B27 antigen a matsayin mai kyau, yayin da kashi 5-10% kawai na yawancin jama'a ke da kyau. Mafi mahimmancin canje-canje a cikin cutar shine fibrosis da ƙarfin ƙasushi. Idan ba a yi magani a kan lokaci ba, yana da sauƙi ya haifar da rashin haɗin gwiwa na marasa lafiya, wahala na rayuwa, saboda haka ana kiran "ciwon daji mara mutuwa". Ƙari ga alamun cututtuka da yawa, gwajin HLA-B27 yana da mahimmanci ga ganewar asali da wuri, magani a kan lokaci, da kuma rigakafi mai kyau.

HLA-B27 Nucleic Acid Test Kit (Fluorescent PCR) da kamfanin ya haɓaka zai iya gano nau'ikan kwayoyin halitta na B2702, B2704, B2705 da ke da alaƙa da AS, wanda zai iya ƙayyade yawan mutanen da ke da alaƙa da AS a cikin yawan mutane na bazuwai; Ga mutanen da ke da tarihin iyali na AS, gwajin HLA-B27 na iya zama daya daga cikin alamun ganewar gargadi na farko na osteoporosis. Ga marasa lafiyar osteoporosis mai ƙarfi da alamun asibiti masu bayyane, gwajin HLA-B27 na iya zama muhimmin taimako ga ganewar asibiti da ganewar ganewa.

Anti tsangwama ikon: Common PCR inhibitors a samfurin kamar lipid, hemoglobin, magunguna da sauransu ba su da tasiri a kan sakamakon gwaji, inganta amincin gwaji

A halin yanzu, dakunan gwaje-gwaje na asibiti ta hanyar fasahar kwayoyin halitta na kwayoyin halitta na HLA-B27 don gano kwayoyin halitta na HLA-B27, wanda ya haɓaka ƙwarewa da takamaiman ganowa, ya rage lokacin ganowa, amma saboda kayan aiki masu tsada, masu aiki da samfurin da ake bincika suna buƙatar ingancin inganci, wanda ya iyakance aikace-aikacen ingantaccen fasahar. Hanyar fluorescent PCR tana da fa'idodi masu ƙarfi, ƙwarewa, sauri da sauransu. Yana ba da damar inganta daidaito da daidaito na gwajin HLA-B27.

Wannan akwatin gwaji tsara ciki ginseng lokaci guda shiga samfurin cirewa, zai iya cimma cikakken rufe amsa tsarin sa ido kan gwajin tsari, yadda ya kamata hana karya m faruwa, tabbatar da daidai da abin dogaro na gwajin sakamakon. Samfurin kafin sarrafawa tare da atomatik na'urar cire nucleic acid da kuma aikin cire reagents, aiki mai sauki da sauri, zai iya rage kuskuren da aka haifar da aikin mutum.

Clinical aikace-aikace

Gwajin HLA-B27 yana taimakawa ganewar AS. HLA-B27 mai kyau a cikin marasa lafiya na AS > 90%, ganewar farko na iya ba da alamun ganewar da ganewar ganewar irin waɗannan marasa lafiya don daidaita rashin rashin ganewar X-ray na AS. Gwajin HLA-B27 ya zama muhimmiyar hanyar ganowa ta asibiti da kuma kimanta haɗarin farko.

Gwajin HLA-B27 na iya hango hanyar komawa ga yara masu cutar da cutar arthritis, yayin da yake da ma'ana ga rigakafin AS.

HLA-B27 a matsayin kwayoyin MHC Class I yana taka muhimmiyar rawa ba kawai a cikin ƙwayoyin cuta da ƙwayoyin cuta ba, har ma yana da wani darajar binciken asibiti.